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Alcoholism is a mental and physical disease characterized by compulsive and uncontrolled consumption of alcohol despite its negative impact on health of the drinker, the drinker interpersonal relationships and his social position. Like other addictions, alcoholism from a medical point of view, is defined as a curable disease. Biological mechanisms of alcoholism includes such factors as social environment, stress, mental health, genetic predisposition age, ethnicity and gender. Prolonged alcohol abuse produces physiological changes in the brain such as tolerance and physical dependence. Such changes in brain chemistry support compulsive inability of the alcoholic to quit drinking and lead to alcoholic withdrawal syndrome upon cessation of drinking. Alcohol damages almost every organ in the body, including the brain. Because of the cumulative toxic effects of chronic alcohol abuse, increased risks of a range of medical and psychiatric disorders. Alcoholism has profound social consequences for alcoholics and their loved ones.