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How do I take my medicine

Medications every day becomes more and more. How, in what cases that take? As a dosage form affects the efficacy of the drug?

Ways of taking the drugs, and especially their action

The most common method of drug administration - oral. In this case, the medicine is swallowed and enters first in the stomach and then into the small intestine, where it is absorbed into the bloodstream. If the drug is taken during a meal, then it is destroyed along with food in the stomach, losing their properties. Therefore, taking pills, at least half an hour before meals or two hours after it. Together with the blood drug enters the liver, where, as a rule, there is an active destruction of virtually any chemical compounds, including drugs.

To avoid splitting the drug in the liver and rapid loss of its properties is widely used method of rectal administration of drugs. Since about a third of the volume of blood moving from the rectum, bypasses the liver, the medicine becomes effective. In this way, introducing a candle or suppositories that are absorbed into the blood as dissolved in the rectum. Rapid-acting drugs can be achieved by the introduction of its aqueous solution enema. Such a method of drug administration is indispensable when the patient is unconscious or stomach no longer take any drugs.

Sometimes, you need not swallow a pill and put it under your tongue. Do so, eg, nitroglycerin for pain in his heart. To some drugs, such as insulin, are not destroyed in the gastrointestinal tract, they are injected under the skin into the muscle or directly into the blood vessel.

There are several ways of introducing drugs into the body: through the respiratory tract (inhalation), skin method (ointments, creams, pastes, powders) and others. In recent years, developed technology targeted transport of drugs, for example when to fight cancer, it is important to achieve the desired concentration right where it is needed.

When to take and what to wash down

The drug three times a day does not mean pre-breakfast, lunch or dinner, and implies - every 8 hours, so the blood is uniformly maintained his concentration. The exceptions are drugs that directly involved in digestion, in the presence of gastro-intestinal diseases.

Medicine is better to wash down with warm boiled water. Tea - little use tool for zapivaniya drugs, since it contained tannin forms many insoluble substances, and therefore pharmacologically inactive compounds. Many drugs can be washed down with warm alkaline mineral waters, and the accelerated penetration of drugs from the stomach into the intestines.

Incompatibility

Known group of drugs that are incompatible with other drugs. For example, the antibiotics tetracycline interaction with calcium ions, aluminum, iron and magnesium (found in large quantities of drugs) is practically not absorbed. Antacids (nominated for a peptic ulcer) also violate the absorption of antibiotics.

Holestirolamin (a drug for lowering blood cholesterol) reduces the absorption of trimethoprim, clindamycin, cephalosporins, tetracyclines, and thyroxine. Absorption of non-steroidal anti-inflammatory drugs (indomethacin, diclofenac) is broken under the action of acetylsalicylic acid. There are many other combinations of incompatible medications.

Not to be mistaken with the drug intake, it is necessary to learn in detail the peculiarities of its action, dosage, compatibility with other medications for a pharmacist in a pharmacy or physician prescribers.

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