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Domperidone prescribed for: Domperidone is a drug used to relieve abdominal discomfort. It is developed by Janssen Pharmaceutical and is distributed under the trade name Motilium. Domperidone is used to treat the common symptoms of abdominal disorders such as nausea and vomiting. Aside from treating digestive problems, Domperidone can also work out effectively in stimulating lactation among woman who had just given birth. However, due to safety concerns, it is hardly advised to be used in increasing breast milk production.