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Lisinopril prescribed for: Lisinopril is a generic medication that also goes by the names Lisihexal, Prinivil, and Zestril. It is part of a class of medications called angiotensin converting inhibitors, or ACE-inhibitors. It is prescribed in tablets for the treatment of several different cardiac conditions. It is given for heart failure to patients who do not respond to other medications. It is given for the treatment of hypertension or high blood pressure, either alone or in conjunction with other medications. It is also given as a treatment for acute myocardial infarction, or heart attack, as part of the course of treatment for the first 24 hours after the attack.