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Risperidone prescribed for: Risperidone is used to treat schizophrenia, bipolar mania [as a sole therapy or combination therapy with lithium (Eskalith, Lithobid) or valproate (Depakene, Depacon) and for the treatment of irritability associated with autistic disorder in children and adolescents. Clinical studies involving small numbers of patients have shown some benefit in using risperidone for stuttering and Tourette syndrome (non FDA-approved uses). Another non-FDA approved use of risperidone is for obsessive-compulsive disorders.